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  • Topical tranexamic acid with microneedling versus microneedling alone in treatment of melasma.

    CLNICAL STUDY

    Background

    Melasma is a disorder of symmetrical hypermelanosis that involves sun-exposed areas of the skin. Although multiple therapeutic treatments have previously been tried, successful & effective treatment for melasma have been few.

    Objective

    To compare the therapeutic effectiveness of topical tranexamic acid (TXA) with microneedling versus microneedling alone in the treatment of melasma.

    Patients & Methods

    This study was conducted on 42 patients with melasma, randomly divided into 2 groups. In group I, each patient was subjected to a series of six sessions of skin microneedling & TXA application. In group II, six sessions of microneedling alone were performed, with 2 week interval.

    Results

    The Melasma area and severity was significantly decreased in both groups with significant higher reduction in group I compared with group II.

    Conclusion

    Although Microneedling alone produced significant lightening effects, topical Tranexamic Acid combined with microneedling achieved more satisfactory results.

    For complete study:   https://journals.lww.com/jewds/fulltext/2019/16020/topical_tranexamic_acid_with_microneedling_versus.3.aspx

     

    Topical Tranexamic Acid

    Derma MD Chebula Tranexamic Acid Face & Neck Serum

    About the Product:

    This lightweight serum formulated with high percentages of clinically proven lightening ingredient Tranexamic Acid. Along with “T” Chebula, combined with Azeglygic Optima, Glutathione & Alpha Arbutin. These ingredients work quickly to improve melasma, pigmentation, lighten dark spots & brighten skin.

    Use with Microneedling

    Patients who received a microneedling treatment for melasma or pigmentation issues along with Tranexamic Acid TXA) will see a significant improvement compared to microneedling on its own.

    Use of Chebula Tranexamic Acid Pigmentation Serum on its own:

    This Serum is formulated with high percentages of a combined group of clinically proven lightening ingredients including Azeglygic Optima Glutathione & Alpha Arbutin.  The combination of these lightening ingredients will work quickly to improve uneven skin tone & lighten pigmentation with daily use.

    How to use at Home:

    Recommended for optimum results & treatment of melasma & pigmentation: Use TXA for 2 weeks prior to microneedling procedure and then use daily after treatment or use nightly without microneedling.

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